Pioneering Biological Dentistry & Regenerative Surgery on Calle de Goya.
Founded & Clinically Directed by Dr. Mariana Espinassi · Colegiada COEM Nº 28007870
In the heart of Barrio de Salamanca, we combine Swiss precision zirconia ceramic implants (100% metal-free), the IAOMT SMART protocol for safe mercury amalgam removal, and ReCODE 2.0 neurocognitive health research in active collaboration with Brain & Body Health Inc. (USA).

COEM Nº 28007870 · Cirujana Biológica
Investigadora en Brain & Body Health Inc. (EE.UU.)


“Dentistry that extends beyond treating teeth to safeguarding systemic health.”
Our commitment is to prevent, diagnose, and treat oral conditions from a biological perspective, considering the direct links between oral health, systemic inflammation, and overall well-being. We combine clinical experience, innovation, and biocompatible materials to provide personalized care grounded in scientific evidence.

Biocompatible Materials
Prioritizing the conservation of natural tissues and bio-inert alternatives.
SMART Protocol (IAOMT)
Safe amalgam removal reducing mercury vapor exposure under strict clinical isolation.
Oral-Systemic Evidence
Evaluating the relationship between oral inflammation and neurocognitive health.
Clinical Case Documentation
Direct intraoral macro photography of actual cases treated at our Calle de Goya practice. No synthetic filters, respecting real enamel translucency and biological gingival seals.
Anterior Monolithic Zirconia Rehabilitation
Replacement of ill-fitting metal crowns with biocompatible ceramic zirconia.



Anterior Ceramic Rehabilitation
Replacement of old metal crowns with bio-inert monolithic zirconia. Natural gum zenith restoration and zero dark margins.

Full Arch Functional Recovery
Fixed provisional crown fitted within 24 hours post-surgery. Restores vertical dimension and facial smile curve balance.

Esthetic Alignment & Porcelain
Micro-alignment followed by ultra-thin stratified porcelain restorations. Preserves natural tooth vitality and light dispersion.
Museum-Grade Archival Certifications
Click any certificate for high-resolution archival inspection with verified credential numbers and institutional seals.

European Active Member & Fellowship
Recognition of surgical excellence in osseointegrated implantology and guided bone regeneration across Europe.

Global Excellence Award in Immediate Load
International honors awarded for biomimetic accuracy and primary stability in 24-hour immediate loading implant protocols.

Center of Dental Excellence
Gold certificate for atraumatic surgical protocols, 3D optical technology, and hospital-grade biological sterility.
Evidence-Based Biological Dentistry
Comprehensive oral health integrated with systemic prevention in Madrid's Barrio de Salamanca.
Biological, Preventive & Oral-Systemic Dentistry
At Instituto Dental Madrid we understand oral health as a fundamental pillar of overall health. Our approach integrates prevention, individualized diagnosis, and identification of infectious and inflammatory processes of oral origin, including periodontal diseases and other pathologies that may influence systemic health. We prioritize the conservation of natural tissues, biocompatible materials, and care based on scientific evidence.

Advanced Implantology & Ceramic Implants
We provide customized oral rehabilitation solutions through advanced implantology, digital planning, and bone regeneration techniques. We work with titanium implants and ceramic alternatives, selecting materials and treatments according to the clinical needs of each patient. Our goal is to recover long-term oral function, stability, and health.

Invisible Orthodontics
Orthodontic treatments using transparent aligners, digital planning, and individualized follow-up. We aim to improve dental alignment, masticatory function, occlusion, and periodontal health, considering the functional and aesthetic needs of each patient.

SMART Protocol - Safe Amalgam Removal
We apply the IAOMT SMART (Safe Mercury Amalgam Removal Technique) protocol to reduce mercury exposure during the removal of dental amalgam restorations. The procedure incorporates specific isolation, suction, and protection measures for the patient and clinical team. Removal is carried out following an individualized dental evaluation when clinically indicated.

Experience, Scientific Updating & Biological Commitment
OVER 25 YEARS OF PROFESSIONAL EXPERIENCE
Career in dentistry, implantology, and oral rehabilitation.
OVER 4,500 IMPLANTS PLACED
Clinical experience in implantology and patient rehabilitation.
INTERNATIONAL TRAINING & CONTINUOUS UPDATING
Participation in continuing education programs, scientific congresses, and international professional organizations.
COMMITMENT TO BIOLOGICAL DENTISTRY
Prevention, biocompatibility, advanced implantology, and oral-systemic focus.
Interactive Clinical Suite
Interact directly with our clinical VITA shade progression and digital 3D optical outcome simulation.
Philips ZOOM! WhiteSpeed® Shade Progression
Slide across the real clinical enamel surface to observe the transition from baseline staining (VITA A3.5) to post-activation luminescence (VITA B1).

Deep coffee, tea and age-related dentin chromogen saturation.

Up to 8 shades whiter with preserved micro-surface natural luster.
Cero calor térmico pulpar
Fosfato de calcio amorfo
pH neutro sin desmineralización
Hasta 24 meses con férula noche
Maxillary Arch Simulation & Occlusal Analytics
Interactive digital dentistry workstation. Inspect tooth-by-tooth FDI positioning, occlusal contact force vectors, and clear aligner staging across 28 treatment steps.
Boutique Medical Environment on Calle de Goya 45
Located opposite the public parking of El Corte Inglés, our clinic is engineered for total serenity and hospital-grade surgical sterility. Featuring private diagnostic suites, HEPA positive-pressure filtration, and 3D digital radiographic tomography.


300+ Verified Patient Experiences
Authentic feedback from Barrio de Salamanca residents and international patients receiving specialized surgical care.
"Traveling from London to Madrid for metal-free zirconia implants with Dra. Mariana Espinassi was the best healthcare decision I have made. Flawless 3D planning, zero post-op swelling, and the surgery suite in Calle de Goya is hospital-grade."
A pleasure taking care of your biological rehabilitation, Charles. The bone integration of the Swiss zirconia has been exemplary.
"I had been looking for a trusted biological dental practice in Madrid for years to safely remove 4 old mercury amalgams. The rigor of the SMART protocol with pure oxygen, non-latex dam, and Clean-Up suction is unmatched. Absolute serenity."
Thank you for your trust, Carmen. Systemic health begins by clearing heavy metals from the oral cavity.
"I fractured an anterior molar while traveling and could not wait 4 months without a fixed tooth for work reasons. Dra. Espinassi performed the atraumatic extraction and fitted my crown in 24 hours. Aesthetically indistinguishable from my natural teeth."
"The Philips ZOOM! chairside whitening lightened my smile by 7 VITA shades in 45 minutes. Best of all: zero thermal sensitivity thanks to the amorphous calcium phosphate (ACP) sealing applied by the doctor."
"As a physician myself, I value technological rigor. The optical iTero 5D scan without silicone impressions and the 1-minute 3D occlusal outcome simulation provided absolute certainty before treatment began."
"I submitted my 3D CBCT scan from Switzerland through their telemedicine portal. Dra. Mariana Espinassi provided a comprehensive video consultation and a metal-free plan that cost 3x as much in Zurich for the exact same Swiss implants."
Request Your Priority Consultation
Includes 3D CT scan, iTero 5D optical impression, and written biological treatment plan without commitment.