Biological Dentistry & Cognitive Longevity in Madrid.
Founded & Clinically Directed by Dr. Mariana Espinassi · Colegiada COEM Nº 28007870
The mouth is not an isolated biome—it is the biological threshold of your neurological and immune health. Directed by Dra. Mariana Espinassi, our practice merges safe mercury amalgam removal under the international IAOMT SMART Protocol, 3D diagnosis of silent jawbone cavitations (NICO/FDOJ), and systemic cognitive health integration in active research collaboration with Brain & Body Health Inc. (USA).

Gabinete equipado para captura de vapores pesados y tomografía 3D en Calle de Goya 45.
Three Scientific Pillars of Biological Dentistry
Moving beyond conventional dentistry to protect your neurological integrity, eliminate silent systemic focal points, and restore balance using strictly biocompatible materials.
IAOMT SMART Amalgam Removal
Standard drilling of mercury amalgams releases hazardous toxic vapor that penetrates systemic tissue. Our Safe Mercury Amalgam Removal Technique (SMART) utilizes hermetic rubber dams, surgical high-volume suction, dedicated oxygen masks, and continuous chilled irrigation to eliminate exposure.
ReCODE 2.0 & Cognitive Health
In partnership with US research foundation Brain & Body Health Inc., Dra. Mariana Espinassi implements the Dr. Dale Bredesen ReCODE protocol to identify oral pathogens (Porphyromonas gingivalis) linked to cognitive decline and chronic neuroinflammation.
NICO / Cavitations Diagnosis & PRF Healing
Silent osteonecrosis in old extraction sites (often wisdom teeth) can produce toxic inflammatory cytokines (RANTES/CCL5). Using sub-millimeter 3D CBCT imaging, we diagnose and debride these ischemic areas, sealing the site with 100% autologous Platelet-Rich Fibrin (PRF) from the patient's own blood.

The 4 Shields of Safe Amalgam Removal
Click through each biological shield to inspect how our Calle de Goya surgical suite isolates mercury.
1. Non-Latex Dental Dam & Absolute Sealing
A non-latex dam sealed with biocompatible barrier isolates the tooth from the oral cavity, tongue, and throat, blocking any particulate ingestion.
The 8-Step IAOMT SMART Safe Mercury Amalgam Extraction Protocol
Extracted directly from Dra. Mariana Espinassi's clinical procedures at Calle de Goya 45 to protect patients and medical personnel from toxic mercury vapor inhalation.
Dedicated Medical Oxygen
Supplemental medical-grade oxygen via external cylinder and nasal cannula to prevent inhaling contaminated ambient air.
Absolute Rubber Dam
Hermetic non-porous rubber dam barrier isolating the treated tooth to prevent accidental swallowing or mucosal absorption.
Activated Carbon Filters
Specialized mercury-vapor capturing respirators and barrier drapes for the patient, surgeon, and surgical nurse.
Closed-Loop Amalgam Trap
Centrifugal amalgam separator and micro-filter network preventing any toxic mercury effluent from entering the water system.
Hazardous Waste Seals
Certified hazardous waste bio-containers for immediate sealing of removed alloy fragments according to European directives.
Dual High-Volume Suction
Continuous negative-pressure surgical high-volume evacuators positioned millimeters from the drill to vacuum vapors at the source.
Section Block Milling
Precision sectioning of the alloy into large blocks using high-speed carbide burs with chilled irrigation to prevent vaporization.
Biological Chelation Support
Pre-, intra-, and post-operative biochemical detoxification with binding agents (activated charcoal and targeted nutrients).
Request Your Priority Consultation
Includes 3D CT scan, iTero 5D optical impression, and written biological treatment plan without commitment.